Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPR1 | P16066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27863466 | 0.71 | OPRM1 (0.38) | BRD4OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL14290430 | 0.70 | PBRM1 (0.37) | PBRM1AHRBLM | |
| SCHEMBL27863497 | 0.68 | SRD5A1 (0.40) | BRD4OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL18107777 | 0.66 | BRD4 (0.47) | BRD4PBRM1ATMMEN1KMT2A | |
| SCHEMBL18114486 | 0.64 | PBRM1 (0.56) | OPRM1OPRD1OPRK1PBRM1AHR | |
| SCHEMBL28000665 | 0.64 | KMT2A (0.37) | BRD4OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL18100258 | 0.63 | OPRM1 (0.45) | BRD4OPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL26956169 | 0.62 | PNMT (0.49) | BRD4OPRM1OPRD1OPRK1HSD17B3 | |
| SCHEMBL19889286 | 0.62 | PBRM1 (0.45) | PBRM1AHRAKR1B1 | |
| SCHEMBL23017164 | 0.61 | BACE1 (0.39) | BRD4ATMAHRTSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107660205-A | Heterocyclic compound as LSD1 inhibitor | 因赛特公司 | 2018-02-02 | — | — | CN | disclosed |