Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113619 | 0.75 | DRD2 (0.53) | CDK2RIPK1DAODRD2DRD4 | |
| SCHEMBL3492565 | 0.74 | DRD2 (0.58) | CDK2RIPK1DAODRD2DRD4 | |
| SCHEMBL24103159 | 0.74 | DAO (0.50) | CDK1RIPK1DAO | |
| SCHEMBL30731038 | 0.74 | MAPT (0.72) | KDM4EMEN1KMT2A | |
| Water SCHEMBL9536491 | 0.72 | RAB9A (0.68) | FABP1FABP6BACE1EGFRPIM1 | |
| SCHEMBL8533229 | 0.72 | GLO1 (0.62) | KDM4ERIPK1MEN1KMT2ADAO | |
| SCHEMBL1413125 | 0.70 | FABP1 (0.67) | NPC1FABP1FABP6BACE1MEN1 | |
| SCHEMBL8536250 | 0.70 | PTGES2 (0.46) | KDM4ERIPK1DAODRD2DRD4 | |
| SCHEMBL5103657 | 0.70 | CDC25B (0.52) | CDC25BKDM4ENPC1EGFRMEN1 | |
| SCHEMBL18415527 | 0.70 | NPC1 (0.76) | KDM4ENPC1L3MBTL1FABP1FABP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |