Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295336 | 1.00 | KDM4E (0.36) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL18802475 | 0.97 | KDM4E (0.35) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL14295335 | 0.95 | KDM4E (0.37) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL14295342 | 0.95 | KDM4E (0.37) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL18327432 | 0.94 | ATM (0.36) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL17637202 | 0.93 | KDM4E (0.35) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL14902057 | 0.93 | KDM4E (0.35) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL12282556 | 0.91 | KDM4E (0.37) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL18904978 | 0.90 | KDM4E (0.32) | KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL14902074 | 0.90 | TSPO (0.34) | KDM4EATML3MBTL1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120319091-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120319091-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120319091-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | INMT, TYR, ALKBH2 | KDM4E 463/4885ATM 769/4885L3MBTL1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.