SCHEMBL14296232

SCHEMBL14296232

CCN(C)CCCN(C)C(=O)[C@H]1CCCC[C@H]1C(=O)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CTSB P07858 1/20 0.31
▸ CTSS P25774 1/20 0.31
▸ CTSK P43235 1/20 0.31
▸ DPP4 P27487 1/20 0.30
▸ KDM5A P29375 1/20 0.30
▸ KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47613 0.89 CHRM2 (0.36) CTSBCTSSCTSK
SCHEMBL47612 0.89 CHRM2 (0.36) CTSBCTSSCTSK
SCHEMBL47607 0.87 SIGMAR1 (0.40) CTSBCTSSCTSK
SCHEMBL47637 0.87 SIGMAR1 (0.40) CTSBCTSSCTSK
SCHEMBL47642 0.83 KMT2A (0.35) CTSBCTSSCTSK
SCHEMBL47611 0.83 KMT2A (0.35) CTSBCTSSCTSK
SCHEMBL18566580 0.81 ADORA1 (0.36) CTSBCTSSCTSK
SCHEMBL99323 0.81 ADORA1 (0.36) CTSBCTSSCTSK
SCHEMBL47599 0.81 ADORA1 (0.36) CTSBCTSSCTSK
SCHEMBL47603 0.81 ADORA1 (0.36) CTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120322721-A1 DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) 2012-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120322721-A1 DRY GROWTH HORMONE COMPOSITION TRANSIENTLY LINKED TO A POLYMER CARRIER GHRHR, GHSR, GCG CTSB 846/4885CTSS 1522/4885CTSK 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback