SCHEMBL14296402

SCHEMBL14296402

O=C(NCCOCCNc1nc(NCCOCCNC(=O)c2ccc(B(O)O)cc2)nc(NCCOCCNC(=O)c2ccc(B(O)O)cc2)n1)c1ccc(B(O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14296399 0.89 SMN1; SMN2 (0.62) SMN1; SMN2
SCHEMBL18532452 0.83 ALDH1A1 (0.57) SMN1; SMN2
SCHEMBL8827862 0.82 SMN1; SMN2 (0.54) SMN1; SMN2
SCHEMBL14296406 0.82 SMN1; SMN2 (0.54) SMN1; SMN2
SCHEMBL17998207 0.80 HPGD (0.57) SMN1; SMN2
SCHEMBL1490749 0.78 HPGD (0.62) SMN1; SMN2
SCHEMBL25231901 0.77 TRPV1 (0.57)
SCHEMBL18356092 0.77 SMN1; SMN2 (0.48) SMN1; SMN2
SCHEMBL18697939 0.74 SMN1; SMN2 (0.44) SMN1; SMN2
SCHEMBL16449276 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296988-B2 Three-dimensional cell adhesion matrix THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-03-29 US disclosed
US-20120322145-A1 THREE-DIMENSIONAL CELL ADHESION MATRIX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-12-20 US disclosed