Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296399 | 0.92 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1CA2NPC1HPGD | |
| SCHEMBL17998207 | 0.87 | HPGD (0.57) | SMN1; SMN2ALDH1A1NPC1HPGDKMT2A | |
| SCHEMBL18532452 | 0.87 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1CA2NPC1HPGD | |
| SCHEMBL8827862 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1CA2NPC1HPGD | |
| SCHEMBL1490749 | 0.84 | HPGD (0.62) | SMN1; SMN2ALDH1A1NPC1HPGDKMT2A | |
| SCHEMBL18356092 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA2NPC1HPGD | |
| SCHEMBL14296402 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL25231901 | 0.81 | TRPV1 (0.57) | ALDH1A1TRPV1 | |
| SCHEMBL13499229 | 0.79 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1NPC1HPGDRAB9A | |
| SCHEMBL18698019 | 0.78 | HPGD (0.70) | SMN1; SMN2ALDH1A1NPC1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296988-B2 | Three-dimensional cell adhesion matrix | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20120322145-A1 | THREE-DIMENSIONAL CELL ADHESION MATRIX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-12-20 | — | — | US | disclosed |