Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296399 | 0.94 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL18698019 | 0.88 | HPGD (0.70) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL14296406 | 0.87 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL8827862 | 0.87 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HPGDNPC1KMT2A | |
| SCHEMBL13499229 | 0.86 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL17998207 | 0.85 | HPGD (0.57) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL14296402 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL1490749 | 0.83 | HPGD (0.62) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL25231901 | 0.82 | TRPV1 (0.57) | ALDH1A1TRPV1TSHR | |
| SCHEMBL18356092 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9572910-B2 | pH responsive self-healing hydrogels formed by boronate-catechol complexation | NORTHWESTERN UNIVERSITY (US) | 2017-02-21 | — | — | US | disclosed |