Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | IL6ST | P40189 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011986 | 1.00 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL17756172 | 1.00 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL8828126 | 0.94 | PPARA (0.40) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL2025733 | 0.92 | KLK7 (0.43) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL8554605 | 0.92 | FAAH (0.40) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL8554608 | 0.92 | FAAH (0.40) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL974301 | 0.92 | KLK7 (0.43) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL6448977 | 0.92 | KLK7 (0.43) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL6448978 | 0.92 | KLK7 (0.43) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL8554613 | 0.92 | FAAH (0.40) | PPARAPLA2G10PLA2G5KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927217-B1 | AMIDE COMPOUND AND PHARMACEUTICAL APPLICATION THEREFOR | JAPAN TOBACCO INC (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2016-12-01 | — | — | US | disclosed |
| EP-2927217-A1 | Amide compound and pharmaceutical application therefor | Japan Tobacco Inc. (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2014-10-02 | — | — | US | disclosed |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346256-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PPARA 303/4885PLA2G10 2717/4885PLA2G5 3002/4885 |
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PPARA 303/4885PLA2G10 2717/4885PLA2G5 3002/4885 |
| US-20140296306-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | PPARA 303/4885PLA2G10 2717/4885PLA2G5 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.