SCHEMBL14299544

SCHEMBL14299544

O=C(O)Cc1ccc2c(c1)C(=O)c1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 6/20 0.58
LMNA P02545 4/20 0.58
MAPT P10636 3/20 0.58
NPC1 O15118 2/20 0.58
ALDH1A1 P00352 2/20 0.58
RAB9A P51151 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MAPK1 P28482 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TTR P02766 1/20 0.53
PTPRC P08575 3/20 0.51
PARK7 Q99497 1/20 0.50
PKLR P30613 1/20 0.50
CTSL P07711 1/20 0.49
PTPN13 Q12923 1/20 0.49
KMT2A Q03164 1/20 0.49
GAA P10253 2/20 0.48
TSHR P16473 2/20 0.48
ABCC4 O15439 1/20 0.48
PTGS1 P23219 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8600926 0.98 AKR1B1 (0.60) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL16091077 0.96 AKR1B1 (0.58) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL19202482 0.93 AKR1B1 (0.58) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL9239083 0.90 AKR1B1 (0.53) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL16091081 0.87 LMNA (0.61) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL4371665 0.84 AKR1B1 (0.51) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL16091071 0.83 LMNA (0.62) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL25137192 0.82 NPC1 (0.58) AKR1B1LMNAMAPTNPC1ALDH1A1
SCHEMBL11680989 0.81 AKR1B1 (0.48) AKR1B1LMNAMAPTPARK7GAA
SCHEMBL27839817 0.81 FFAR1 (0.56) LMNAMAPTNPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10359713-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-07-23 US disclosed
US-9890244-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators SUMITOMO BAKELITE CO., LTD. (JP) 2018-02-13 US disclosed
US-9890244-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators SUMITOMO BAKELITE CO., LTD. (JP) 2018-02-13 US disclosed
US-9757818-B2 Thermally decomposable polymer compositions for forming microelectronic assemblies PROMERUS, LLC (US) 2017-09-12 US disclosed
US-9757818-B2 Thermally decomposable polymer compositions for forming microelectronic assemblies PROMERUS, LLC (US) 2017-09-12 US disclosed
US-9690196-B2 Photoimageable compositions containing thermal base generators PROMERUS, LLC (US) 2017-06-27 US disclosed
US-9690196-B2 Photoimageable compositions containing thermal base generators PROMERUS, LLC (US) 2017-06-27 US disclosed
US-9637565-B2 Photoinitiating system for anionic polymerization UVIC INDUSTRY PARTNERSHIPS INC. (US) 2017-05-02 US disclosed
US-9637565-B2 Photoinitiating system for anionic polymerization UVIC INDUSTRY PARTNERSHIPS INC. (US) 2017-05-02 US disclosed
US-20170036308-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS FOR FORMING MICROELECTRONIC ASSEMBLIES PROMERUS, LLC (US) 2017-02-09 US disclosed
US-20150299509-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS FOR FORMING MICROELECTRONIC ASSEMBLIES PROMERUS, LLC (US) 2015-10-22 US disclosed
US-20150299509-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS FOR FORMING MICROELECTRONIC ASSEMBLIES PROMERUS, LLC (US) 2015-10-22 US disclosed
US-9115300-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators PROMERUS, LLC 2015-08-25 US disclosed
US-9115300-B2 Thermally decomposable polymer compositions incorporating thermally activated base generators PROMERUS, LLC 2015-08-25 US disclosed
US-20140275316-A1 PHOTOINITIATING SYSTEM FOR ANIONIC POLYMERIZATION UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2014-09-18 US disclosed
US-20140275316-A1 PHOTOINITIATING SYSTEM FOR ANIONIC POLYMERIZATION UVIC INDUSTRY PARTNERSHIPS INC. (CA) 2014-09-18 US disclosed
WO-2014099614-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITION FOR FORMING MICROELECTRIC ASSEMBLIES PROMERUS, LLC (US) 2014-06-26 WO disclosed
US-20120318854-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS LLC (US) 2012-12-20 US disclosed
US-20120318854-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS LLC (US) 2012-12-20 US disclosed
WO-2012174384-A1 THERMALLY DECOMPOSABLE POLYMER COMPOSITIONS INCORPORATING THERMALLY ACTIVATED BASE GENERATORS PROMERUS LLC (US) 2012-12-20 WO disclosed