Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600926 | 0.91 | AKR1B1 (0.60) | AKR1B1LMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL14299544 | 0.90 | AKR1B1 (0.58) | AKR1B1LMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL19202482 | 0.89 | AKR1B1 (0.58) | AKR1B1LMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL16091077 | 0.86 | AKR1B1 (0.58) | AKR1B1LMNAMAPTNPC1ALDH1A1 | |
| SCHEMBL4371665 | 0.81 | AKR1B1 (0.51) | AKR1B1LMNAMAPTNPC1ALDH1A1 | |
| 2-Naphthylacetic Acid SCHEMBL28641469 | 0.78 | NR1H4 (0.71) | AKR1B1LMNAMAPTNR1H4PTGS1 | |
| 2-Naphthylacetic Acid SCHEMBL29366514 | 0.78 | NR1H4 (0.71) | AKR1B1LMNAMAPTNR1H4PTGS1 | |
| 2-Naphthylacetic Acid SCHEMBL238445 | 0.78 | NR1H4 (0.71) | AKR1B1LMNAMAPTNR1H4PTGS1 | |
| 2-Naphthylacetic Acid SCHEMBL30493868 | 0.78 | NR1H4 (0.71) | AKR1B1LMNAMAPTNR1H4PTGS1 | |
| SCHEMBL11767982 | 0.78 | PTGS1 (0.54) | AKR1B1LMNAMAPTALDH1A1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391749-A | Photoinitiators or photosensitizers | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| US-5112977-A | Photoinitiators, metallization of polymeric surfaces | CIBA-GEIGY CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |