Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609958 | 0.95 | ESR1 (0.53) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL11653228 | 0.88 | ESR1 (0.52) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL31240951 | 0.88 | ESR1 (0.52) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL95477 | 0.86 | CA1 (0.58) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL13856749 | 0.84 | ESR1 (0.57) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL13135102 | 0.84 | ALDH1A1 (0.53) | ESR1CYP3A4HPGDARSLC6A2 | |
| SCHEMBL4397432 | 0.82 | CA12 (0.65) | ESR1ESR2CYP3A4HPGDAR | |
| SCHEMBL6581882 | 0.82 | HSP90AA1 (0.60) | HPGDHSD17B10ALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL13609970 | 0.81 | ESR1 (0.43) | ESR1CYP3A4HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10464291 | 0.80 | CSNK2A1 (0.55) | ESR1ESR2CYP3A4HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838979-A1 | MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES | Covestro Deutschland AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| WO-2008021673-A1 | POLYSILOXANE COPOLYMERS,THERMOPLASTIC COMPOSITION, AND ARTICLES FORMED THEREFROM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-02-21 | — | — | WO | disclosed |