Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609958 | 0.89 | ESR1 (0.53) | ALDH1A1HPGDMAPK1CYP3A4HTT | |
| SCHEMBL9677356 | 0.88 | MAPT (0.50) | ALDH1A1HPGDMAPK1CYP3A4P2RX1 | |
| SCHEMBL13623209 | 0.88 | CYP3A4 (0.66) | ALDH1A1HPGDMAPK1CYP3A4HTT | |
| SCHEMBL4395924 | 0.87 | CA1 (0.53) | ALDH1A1HPGDMAPK1CYP3A4P2RX1 | |
| SCHEMBL14301487 | 0.84 | ESR1 (0.55) | ALDH1A1HPGDMAPK1CYP3A4P2RX1 | |
| SCHEMBL31240951 | 0.83 | ESR1 (0.52) | ALDH1A1HPGDCYP3A4ESR1MAPT | |
| SCHEMBL11653228 | 0.83 | ESR1 (0.52) | ALDH1A1HPGDCYP3A4ESR1MAPT | |
| SCHEMBL15831655 | 0.82 | KLF10 (0.41) | ALDH1A1HPGDMAPK1CYP3A4P2RX1 | |
| SCHEMBL4383880 | 0.81 | MAPT (0.50) | ALDH1A1HPGDMAPK1CYP3A4NPC1 | |
| SCHEMBL63554 | 0.81 | KDM4E (0.47) | ALDH1A1HTTNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002429-A1 | POLYMERIC SHEETS, METHODS FOR MAKING AND USING THE SAME, AND ARTICLES COMPRISING POLYMERIC SHEETS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-07 | — | — | US | disclosed |
| US-7790292-B2 | Polysiloxane copolymers, thermoplastic composition, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-09-07 | — | — | US | disclosed |
| US-7700696-B2 | Polycarbonate composition having improved scratch resistance, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-04-20 | — | — | US | disclosed |
| US-7326764-B2 | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | GENERAL ELECTRIC COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7323536-B2 | Reaction product obtained by melt blending an aromatic polyester-polycarbonate and a transesterification catalyst that has a haze of less than 5.0% | GENERAL ELECTRIC COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323535-B2 | Reaction product obtained by melt blending an aromatic polyester-polycarbonate, a polycarbonate and a transesterification catalyst that has a haze of less than 1.0% | GENERAL ELECTRIC COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20080004404-A1 | THERMOPLASTIC COMPOSITION HAVING IMPROVED SCRATCH RESISTANCE, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-01-03 | — | — | US | disclosed |
| US-7273917-B2 | Transparent compositions, methods for the preparation thereof, and articles derived therefrom | GENERAL ELECTRIC COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070129492-A1 | POLYSILOXANE COPOLYMERS, THERMOPLASTIC COMPOSITION, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070027268-A1 | Reaction product obtained by melt blending two aromatic polyester-polycarbonates and a transesterification catalyst that has a haze of less than 1.0% | GENERAL ELECTRIC COMPANY (US) | 2007-02-01 | — | — | US | disclosed |