Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401482 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL4110436 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899944 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16340705 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15165006 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15910017 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL4110433 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL13903997 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL8747631 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899946 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229891-A1 | NOVEL IMMUNODULATING SMALL MOLECULES | AYUVIS RESEARCH, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023009567-A1 | COMPOSITONS AND METHODS FOR THE TREATMENT OF BRONCHOPULMONARY DYSPLASIA (BPD) AND BPD-ASSOCIATED PULMONARY HYPERTENSION | AYUVIS RESEARCH, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| US-20230000887-A1 | Novel Immunodulating Small Molecules | AYUVIS RESEARCH, INC. | 2023-01-05 | — | — | US | disclosed |
| US-9145440-B2 | Versatile native chemical ligation technologies | WASHINGTON STATE UNIVERSITY (US) | 2015-09-29 | — | — | US | disclosed |
| US-20140213758-A1 | VERSATILE NATIVE CHEMICAL LIGATION TECHNOLOGIES | WASHINGTON STATE UNIVERSITY (US) | 2014-07-31 | — | — | US | disclosed |
| WO-2008001109-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS | UCL BUSINESS PLC (GB) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000887-A1 | Novel Immunodulating Small Molecules | MSR1, NR4A3, NR4A2 | LMNA 4883/4885KMT2A 2288/4885POLB 3916/4885 |
| US-20140213758-A1 | VERSATILE NATIVE CHEMICAL LIGATION TECHNOLOGIES | PTMS, DNPEP, OGT | LMNA 4234/4885KMT2A 2459/4885POLB 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.