Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302583 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL4110436 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899944 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16340705 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15165006 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15910017 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL4110433 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL13903997 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL8747631 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899946 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249063-A1 | Biosensors | UNIVERSITY OF MARYLAND | 2007-10-25 | — | — | US | disclosed |