Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401482 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL14302583 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899944 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL16340705 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15165006 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL15910017 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL4110433 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL13903997 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL8747631 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 | |
| SCHEMBL7899946 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075396-A1 | Biosensors | UNIVERSITY OF MARYLAND OFFICE OF TECHNOLOGY COMMERCIALIZATION (US) | 2009-03-19 | — | — | US | disclosed |
| US-20070249063-A1 | Biosensors | UNIVERSITY OF MARYLAND | 2007-10-25 | — | — | US | disclosed |
| US-5808059-A | CHROMATOGRAPHY; ELECTROPHORESIS | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 1998-09-15 | — | — | US | disclosed |
| US-5744302-A | USING A PORPHYRIN; COMPLEXING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-04-28 | — | — | US | disclosed |
| US-5696082-A | INHIBITORS OF MATRIX METALLOPROTEINASES AND OF THE PRODUCTION OF TUMOR NECROSIS FACTOR | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-12-09 | — | — | US | disclosed |
| US-5672490-A | PROMOTING THE SPLITTING DNA BY MIXING WITH A SAPPHYRIN-EDTA CONJUGATE COMPOUND | THE UNIVERSITY OF TEXAS BOARD OF REGENTS (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0694036-B1 | HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 1997-03-05 | — | — | EP | disclosed |
| US-5556941-A | ANTICOAGULANTS, THROMBIN INHIBITORS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |
| US-5543514-A | Water-soluble sapphyrins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-08-06 | — | — | US | disclosed |
| US-5530123-A | ANTIVIRAL AND CHEMOTHERAPEUTICAL AGENT FOR CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1996-06-25 | — | — | US | disclosed |
| US-5457195-A | Sapphyrin derivatives and conjugates | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0413675-B1 | Method for producing synthetic N-linked glycoconjugates | MONSANTO CO (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994009003-A1 | SAPPHYRIN DERIVATIVES, CONJUGATES AND POLYMERS THEREOF AND EXPANDED PORPHYRIN CHROMATOGRAPHIC SUPPORTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5091523-A | Bactericides, antitumor agent | GEORGETOWN UNIVERSITY (US) | 1992-02-25 | — | — | US | disclosed |
| US-4157439-A | ANTITUMOR, LOW TOXICITY, NONHYDROLYZING | SUAMI T (JP) | 1979-06-05 | — | — | US | disclosed |