Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303169 | 0.85 | TYR (0.49) | TERTSTAT3HIF1ACYP1B1MAPT | |
| SCHEMBL14302833 | 0.82 | TERT (0.50) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL14302826 | 0.82 | TERT (0.54) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL14303160 | 0.79 | TOP2A (0.60) | TERTSTAT3HIF1AKCNH2MEN1 | |
| SCHEMBL29361586 | 0.78 | ALDH1A1 (0.67) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL1630714 | 0.78 | ALDH1A1 (0.67) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL31257229 | 0.76 | TERT (0.53) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL14303166 | 0.76 | TERT (0.53) | TERTSTAT3HIF1ACYP1B1RAB9A | |
| SCHEMBL17260644 | 0.75 | MAPT (0.55) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12431369 | 0.75 | TERT (0.49) | TERTCYP1B1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977754-B1 | WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |