Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | TERT | O14746 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302826 | 0.82 | TERT (0.54) | TOP2AKDM4EGAARECQLTERT | |
| SCHEMBL14303163 | 0.80 | GAA (0.62) | TOP2AAPPBCHEACHEKDM4E | |
| SCHEMBL14303137 | 0.79 | TERT (0.50) | TOP2AKDM4EGAARECQLTERT | |
| SCHEMBL14302833 | 0.79 | TERT (0.50) | ACHEGAATERTMEN1KMT2A | |
| SCHEMBL1630714 | 0.75 | ALDH1A1 (0.67) | KDM4EGAATERTMEN1KMT2A | |
| SCHEMBL12431369 | 0.75 | TERT (0.49) | TOP2AKDM4EGAARECQLTERT | |
| SCHEMBL29361586 | 0.75 | ALDH1A1 (0.67) | KDM4EGAATERTMEN1KMT2A | |
| SCHEMBL29263694 | 0.75 | MAOB (0.69) | TOP2AAPPBCHEACHEMAOB | |
| SCHEMBL14524630 | 0.75 | HEXA (0.56) | KDM4EGAATERTSIGMAR1MEN1 | |
| SCHEMBL18378925 | 0.73 | APP (0.53) | TOP2AAPPBCHEACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977754-B1 | WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |