Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | TACR2 | P21452 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TST | Q16762 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941872 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27362553 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2615717 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9717309 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL13564082 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2615718 | 0.98 | ESR1 (0.63) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Ammonia Solution, Strong SCHEMBL7005637 | 0.96 | ESR1 (0.61) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Ethyne SCHEMBL27743285 | 0.96 | ALDH1A1 (0.55) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8037699 | 0.94 | RARB (0.58) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| Methyl Alcohol SCHEMBL27692953 | 0.94 | ESR1 (0.64) | ALDH1A1ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060177742-A1 | Nonaqueous electrolytic solution for lithium secondary battery and lithium secondary battery using the same | MU IONIC SOLUTIONS CORPORATION (JP) | 2006-08-10 | — | — | US | claimed |
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | claimed |
| US-4025512-A | ANTIDEPRESSANTS | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | claimed |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2023-10-05 | — | — | US | disclosed |
| US-20230127965-A1 | METHODS FOR TREATING, AMELIORATING, OR PREVENTING VIRAL INFECTIONS | UNIV JEFFERSON (US) | 2023-04-27 | — | — | US | disclosed |
| US-11584852-B2 | Compound and colored resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-02-21 | — | — | US | disclosed |
| US-11572364-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210002487-A1 | COMPOUND AND COLORED RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-01-07 | — | — | US | disclosed |
| CN-111320646-A | 1, 4-eneyne compound and preparation method and application thereof | 广东工业大学 | 2020-06-23 | — | — | CN | disclosed |
| EP-3533470-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | Kyoto University (JP) | 2019-09-04 | — | — | EP | disclosed |
| CN-109872830-A | Production method for the surface modifier of metal electrode, surface-modified metal electrode and surface-modified metal electrode | 信越化学工业株式会社 | 2019-06-11 | — | — | CN | disclosed |
| US-5814651-A | PHOSPHODIESTERASE TYPE FOUR INHIBITORS | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |
| CN-1038586-C | Pyrazine derivatives and process for preparing same | OTSUKA PHARMA CO LTD (JP) | 1998-06-03 | — | — | CN | disclosed |
| CN-1150799-A | Benzoheterocyclic derivatives | OTSUKA PHARMA CO LTD (JP) | 1997-05-28 | — | — | CN | disclosed |
| CN-1112364-A | Piperazine derivatives and salts thereof | OTSUKA PHARMA CO LTD (JP) | 1995-11-22 | — | — | CN | disclosed |
| CN-1104412-A | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 1995-06-28 | — | — | CN | disclosed |
| CN-1094028-A | Selective PDE enzyme (IV) inhibitor catechol diether class | PFIZER (US) | 1994-10-26 | — | — | CN | disclosed |
| CN-1067053-A | Pyrazines derivatives and preparation method thereof | OTSUKA PHARMA CO LTD (JP) | 1992-12-16 | — | — | CN | disclosed |
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |
| US-4096265-A | HYPOTENSIVE AGENTS | SHARPS ASSOCIATES (US) | 1978-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | ALDH1A1 569/4885ESR1 2409/4885ADRA2A 4382/4885 |
| US-20230127965-A1 | METHODS FOR TREATING, AMELIORATING, OR PREVENTING VIRAL INFECTIONS | TMEM97, SIGMAR1, OPRL1 | ALDH1A1 619/4885ESR1 971/4885ADRA2A 44/4885 |
| US-11584852-B2 | Compound and colored resin composition | H1-0, HRH3, HRH4 | ALDH1A1 1902/4885ESR1 1650/4885ADRA2A 1329/4885 |
| US-20210002487-A1 | COMPOUND AND COLORED RESIN COMPOSITION | H1-0, HRH3, HRH4 | ALDH1A1 1902/4885ESR1 1650/4885ADRA2A 1329/4885 |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | ALDH1A1 569/4885ESR1 2409/4885ADRA2A 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.