Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | TST | Q16762 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13564082 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL9717309 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL27362553 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL2615718 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL2615717 | 1.00 | ESR1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL7005637 | 0.98 | ESR1 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL1430472 | 0.98 | ALDH1A1 (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Methyl Alcohol SCHEMBL27692953 | 0.96 | ESR1 (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL8052463 | 0.94 | HSD17B10 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10929094 | 0.94 | HSD17B10 (0.61) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180318816-A1 | METAL ORGANIC FRAMEWORKS, THEIR SYNTHESIS AND USE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2018-11-08 | — | — | US | claimed |
| WO-2018204602-A1 | METAL ORGANIC FRAMEWORKS, THEIR SYNTHESIS AND USE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2018-11-08 | — | — | WO | claimed |
| US-12091595-B2 | Curable organopolysiloxane release agent composition for thermal paper, thermal paper, and thermal recording label sheet | DOW TORAY CO., LTD. (JP) | 2024-09-17 | — | — | US | disclosed |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230339891-A1 | URACIL DERIVATIVES AS MER-AXL INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-26 | — | — | US | disclosed |
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-20210189193-A1 | CURABLE ORGANOPOLYSILOXANE RELEASE AGENT COMPOSITION FOR THERMAL PAPER, THERMAL PAPER, AND THERMAL RECORDING LABEL SHEET | DOW TORAY CO., LTD. (JP) | 2021-06-24 | — | — | US | disclosed |
| EP-2968211-B1 | PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME | BIO PHARM SOLUTIONS CO LTD (KR) | 2021-05-12 | — | — | EP | disclosed |
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2021-04-22 | — | — | US | disclosed |
| CN-109096046-B | Preparation method of halogenated alkane synthesized from styrene and derivatives thereof and trichloroalkane | 温州大学 | 2021-03-02 | — | — | CN | disclosed |
| US-7763610-B2 | Carboxylic acid derived benzoxazines as agents for the treatment of respiratory diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-2046746-A2 | CHEMICAL COMPOUNDS | Praecis Pharmaceuticals Incorporated (US) | 2009-04-15 | — | — | EP | disclosed |
| CN-101292380-A | Lithium ion batteries | ALTAIRNANO INC (US) | 2008-10-22 | — | — | CN | disclosed |
| WO-2008016692-A2 | CHEMICAL COMPOUNDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-02-07 | — | — | WO | disclosed |
| CN-1524068-A | Perfluoroalkylphenol stain resists | 纳幕尔杜邦公司 | 2004-08-25 | — | — | CN | disclosed |
| CN-1058963-C | Triazole derivative, insecticidal/acaricidal agent, and process for producing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1197452-A | Azetidinone derivatives for treatment of atherosclerosis | SMITHKLINE BEECHAM PLC (GB) | 1998-10-28 | — | — | CN | disclosed |
| EP-0686151-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-13 | — | — | EP | disclosed |
| CN-1105179-A | Triazole derivative, insecticidal/acaricidal agent, and process for producing the same | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1995-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | ESR1 4046/4885ADRA2A 4677/4885ADORA3 4806/4885 |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | MERTK, DAPK1, AXL | ESR1 3002/4885ADRA2A 3920/4885ADORA3 692/4885 |
| US-11225480-B2 | Malic enzyme inhibitors | ME1, RNASE1, ME2 | ESR1 3778/4885ADRA2A 3680/4885ADORA3 4659/4885 |
| US-20210403462-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | DDT, ACHE, NIT2 | ESR1 3481/4885ADRA2A 1197/4885ADORA3 1175/4885 |
| US-20230339891-A1 | URACIL DERIVATIVES AS MER-AXL INHIBITORS | MERTK, DAPK1, AXL | ESR1 3002/4885ADRA2A 3920/4885ADORA3 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.