Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280271 | 0.84 | ALDH1A1 (0.44) | TYRALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL14280250 | 0.84 | KMT2A (0.38) | TYRALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL14306732 | 0.83 | ALDH1A1 (0.36) | TYRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14280256 | 0.80 | VCAM1 (0.41) | TYRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14280246 | 0.80 | ALDH1A1 (0.42) | TYRABCC1ACHEALDH1A1KMT2A | |
| SCHEMBL14306630 | 0.77 | TYR (0.41) | TYRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14280245 | 0.70 | MEN1 (0.45) | TYRALDH1A1KMT2AMEN1PTGS2 | |
| SCHEMBL14280247 | 0.68 | KMT2A (0.45) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL12680494 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL14280268 | 0.68 | KMT2A (0.44) | ACHEALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |