Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280242 | 0.88 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1CYP1A2TSHR | |
| SCHEMBL14306621 | 0.87 | ALDH1A1 (0.36) | KMT2AALDH1A1MEN1CYP1A2MAPT | |
| SCHEMBL14280243 | 0.84 | VCAM1 (0.41) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL14280240 | 0.84 | SMN1; SMN2 (0.41) | KMT2AALDH1A1MEN1CYP1A2MAPT | |
| SCHEMBL14280271 | 0.83 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1CYP1A2TSHR | |
| SCHEMBL13580425 | 0.81 | PTPRC (0.40) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13580843 | 0.79 | NPC1 (0.33) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13580329 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1MEN1CYP1A2TSHR | |
| SCHEMBL13580331 | 0.77 | KMT2A (0.34) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL14280269 | 0.76 | NPC1 (0.37) | KMT2AALDH1A1MAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |