Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 14/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305552 | 0.94 | GUCY1A1 (0.48) | HTR4CYP3A4CYP2D6GUCY1A1GUCY1B1 | |
| SCHEMBL14313787 | 0.84 | HTR4 (0.45) | HTR4CYP3A4CYP2D6CNR2CNR1 | |
| SCHEMBL3899250 | 0.79 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL14305551 | 0.76 | HTR4 (0.41) | HTR4CYP3A4CYP2D6CNR2CNR1 | |
| SCHEMBL9532171 | 0.75 | HTR4 (0.59) | HTR4CYP3A4CYP2D6 | |
| SCHEMBL3897724 | 0.73 | GUCY1A1 (0.55) | GUCY1A1GUCY1B1CNR2 | |
| SCHEMBL9532340 | 0.73 | HTR3A (0.59) | HTR4CYP3A4CYP2D6 | |
| SCHEMBL3901927 | 0.73 | CNR2 (0.57) | GUCY1A1GUCY1B1CNR2CNR1 | |
| SCHEMBL3909953 | 0.70 | GUCY1A1 (0.52) | HTR4GUCY1A1GUCY1B1CNR2CNR1 | |
| SCHEMBL14305553 | 0.69 | HTR4 (0.46) | HTR4CYP3A4CYP2D6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008005908-A2 | PYRIDOIMIDAZOLE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-01-10 | — | — | WO | disclosed |