Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12620725 | 0.81 | TSHR (0.45) | TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14306357 | 0.77 | PAX8 (0.32) | PAX8TP53ACHETSHR | |
| SCHEMBL10268170 | 0.77 | GBA1 (0.36) | CYP2D6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23267575 | 0.76 | CHRNA7 (0.33) | — | |
| SCHEMBL13849461 | 0.76 | CHRNA7 (0.33) | — | |
| SCHEMBL2271063 | 0.76 | CHRNA7 (0.33) | — | |
| SCHEMBL22273332 | 0.75 | HSD11B1 (0.46) | PAX8TP53ACHETSHRCYP2D6 | |
| SCHEMBL21287906 | 0.75 | ATM (0.36) | PAX8TP53 | |
| SCHEMBL16512308 | 0.74 | ACHE (0.41) | PAX8TP53ACHETSHRSMN1; SMN2 | |
| SCHEMBL15871709 | 0.73 | CYP2D6 (0.35) | PAX8CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154683-A1 | METHODS OF TREATING DISEASE WITH MAGL INHIBITORS | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2020-07-30 | — | — | WO | disclosed |
| WO-2012171863-A1 | NEW SELECTIVE CCR2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | WO | disclosed |