Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306626 | 0.79 | POLB (0.37) | POLBGPR55 | |
| SCHEMBL14315017 | 0.75 | POLB (0.34) | MAPTPOLBGPR55ALDH1A1 | |
| SCHEMBL14315022 | 0.73 | POLB (0.37) | POLBGPR55 | |
| SCHEMBL14315019 | 0.71 | POLB (0.43) | POLBGPR55SMN1; SMN2 | |
| SCHEMBL5355231 | 0.62 | ENPP2 (0.75) | MAPTPOLBENPP2PTGS2PTGS1 | |
| SCHEMBL5355235 | 0.62 | ENPP2 (0.75) | MAPTPOLBENPP2PTGS2PTGS1 | |
| SCHEMBL13886742 | 0.62 | POLB (0.53) | MAPTPOLBGPR55ALDH1A1SMN1; SMN2 | |
| SCHEMBL2376239 | 0.61 | ENPP2 (0.72) | ENPP2PTGS2 | |
| SCHEMBL21882103 | 0.61 | MAPT (0.44) | MAPTPOLBENPP2PTGS2CA12 | |
| SCHEMBL7056902 | 0.60 | ENPP2 (0.52) | MAPTENPP2PTGS2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |