Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.75 |
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | GLB1 | P16278 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355235 | 1.00 | ENPP2 (0.75) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL1535 | 0.87 | ENPP2 (1.00) | ENPP2CA12CA2CA9LMNA | |
| SCHEMBL5357289 | 0.84 | ENPP2 (0.53) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL5357284 | 0.84 | ENPP2 (0.53) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL5350472 | 0.82 | ENPP2 (0.50) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL5350477 | 0.82 | ENPP2 (0.50) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL4808253 | 0.81 | LMNA (0.74) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL2171353 | 0.81 | LMNA (0.74) | ENPP2CA12CA2CA9CA7 | |
| SCHEMBL7940666 | 0.80 | ENPP2 (0.86) | ENPP2CA12CA2CA9LMNA | |
| SCHEMBL388018 | 0.80 | ENPP2 (0.86) | ENPP2CA12CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197699-A1 | Novel substituted-polyaryl chromophoric compounds | TRANSPHOTONICS, LLC (US) | 2007-08-23 | — | — | US | disclosed |
| US-7205347-B2 | Substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, LLC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20040013375-A1 | Novel substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, L.L.C. | 2004-01-22 | — | — | US | disclosed |
| WO-2002033005-A2 | NOVEL SUBSTITUTED-POLYARYL CHROMOPHORIC COMPOUNDS | TRANS PHOTONICS, L.L.C. (US) | 2002-04-25 | — | — | WO | disclosed |