Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308003 | 0.80 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL12937374 | 0.78 | TOP1 (0.74) | HSP90AA1HSP90AB1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17803600 | 0.78 | RAB9A (0.57) | CA9RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL27613759 | 0.77 | MAPK1 (0.62) | CA9RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL16964304 | 0.77 | KDM4E (0.61) | RAB9ANPC1KDM4EMAPTGABRP | |
| SCHEMBL14062132 | 0.77 | LMNA (0.62) | RAB9ANPC1LMNAKDM4EMAPT | |
| SCHEMBL12764177 | 0.75 | MAPK14 (0.65) | — | |
| SCHEMBL10242069 | 0.75 | KMT2A (0.71) | HSP90AA1HSP90AB1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17803591 | 0.75 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL17831484 | 0.74 | KCNK3 (0.71) | HSP90AA1HSP90AB1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878727-A1 | 2-AMINOQUINAZOLINE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-16 | — | — | EP | disclosed |