Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | NT5E | P21589 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14062132 | 0.87 | LMNA (0.62) | KDM4EHTTJAK2TYK2NPC1 | |
| SCHEMBL24010215 | 0.86 | KCNK3 (0.58) | KDM4EHTTJAK2TYK2NT5E | |
| SCHEMBL27613759 | 0.84 | MAPK1 (0.62) | KDM4EGAAKMT2AMEN1JAK2 | |
| SCHEMBL1898755 | 0.80 | GAA (0.91) | KDM4EGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL16702237 | 0.80 | HTT (0.55) | GAAL3MBTL1KMT2AMEN1HTT | |
| SCHEMBL10483323 | 0.79 | GABRP (0.53) | KDM4EGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL17803600 | 0.79 | RAB9A (0.57) | NPC1RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL2955207 | 0.79 | KDM4E (0.68) | KDM4EGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL19774543 | 0.79 | KDM4E (0.80) | KDM4EGAAL3MBTL1KMT2AMEN1 | |
| SCHEMBL14308003 | 0.78 | MEN1 (0.66) | KDM4EKMT2AMEN1HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11427566-B2 | Compounds useful for treating cancer | ABIVAX (FR) | 2022-08-30 | — | — | US | disclosed |
| US-20200239444-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | ABIVAX (FR) | 2020-07-30 | — | — | US | disclosed |
| US-10717724-B2 | Compounds useful for treating cancer | ABIVAX (FR) | 2020-07-21 | — | — | US | disclosed |
| US-20180222888-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | ABIVAX (FR) | 2018-08-09 | — | — | US | disclosed |
| US-9969715-B2 | Compounds useful for treating cancer | ABIVAX (FR) | 2018-05-15 | — | — | US | disclosed |
| EP-2900635-B1 | NEW ANTI-INVASIVE COMPOUNDS | ABIVAX (FR) | 2016-07-13 | — | — | EP | disclosed |
| US-20150315173-A1 | NEW ANTI-INVASIVE COMPOUNDS | UNIVERSITE DE MONTPELLIER (FR) | 2015-11-05 | — | — | US | disclosed |
| EP-2900635-A1 | NEW ANTI-INVASIVE COMPOUNDS | ABIVAX (FR) | 2015-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180222888-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | PRMT7, PRMT6, RRM2 | KDM4E 1436/4885GAA 4810/4885L3MBTL1 1527/4885 |
| US-20150315173-A1 | NEW ANTI-INVASIVE COMPOUNDS | MIF, MMP7, MMP8 | KDM4E 2252/4885GAA 4616/4885L3MBTL1 2247/4885 |
| US-10717724-B2 | Compounds useful for treating cancer | PRMT7, PRMT6, RRM2 | KDM4E 1436/4885GAA 4810/4885L3MBTL1 1527/4885 |
| US-20200239444-A1 | COMPOUNDS USEFUL FOR TREATING CANCER | PRMT7, PRMT6, RRM2 | KDM4E 1246/4885GAA 4834/4885L3MBTL1 1595/4885 |
| US-11427566-B2 | Compounds useful for treating cancer | PRMT7, PRMT6, RRM2 | KDM4E 1246/4885GAA 4834/4885L3MBTL1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.