Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21121950 | 0.82 | ALDH1A1 (0.51) | GAAALDH1A1EPHX1SMN1; SMN2HPGD | |
| SCHEMBL2095490 | 0.80 | TAAR1 (0.69) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL2095487 | 0.79 | NPC1 (0.58) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL22282200 | 0.79 | NPC1 (0.58) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL28277097 | 0.79 | TAAR1 (0.58) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL28203595 | 0.79 | NPC1 (0.58) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL28010694 | 0.79 | NPC1 (0.58) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL12582415 | 0.79 | HTT (0.54) | GAAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23120896 | 0.78 | HDAC3 (0.52) | NPC1RAB9ATAAR1GAACA12 | |
| SCHEMBL19387598 | 0.77 | NPC1 (0.56) | NPC1RAB9ATAAR1GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109966240-A | The subcutaneously composition and method of fatty local delivery prostaglandin | 托普凯恩制药公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106133004-B | Catalyst component for olefin polymerization | 巴塞尔聚烯烃意大利有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-105209015-B | Compositions and methods for local delivery of prostaglandins to subcutaneous fat | 托普凯恩制药公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-104718202-B | The method for being used to prepare (S) -3- (4- ((4- (morpholinyl methyl) benzyl) oxygroup) -1- oxoisoindolines -2- base) piperidine-2,6-diones and its pharmaceutically acceptable form | 细胞基因公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-108779460-A | Multiplexing using microparticles in dispensing | 睿恩达思技术公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104640540-B | Enhanced anti-influenza agents coupled with anti-inflammatory activity | 中央研究院 | 2018-10-09 | — | — | CN | disclosed |
| CN-104010643-B | Methods and compositions for reducing body fat and adipocytes | 托普凯恩制药公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-104024278-B | Modificationization polyrotaxane and manufacture method thereof and there is modificationization polyrotaxane and the material that formed | 高级软质材料株式会社 | 2016-10-26 | — | — | CN | disclosed |
| CN-106029653-A | Diaminopyrimidine benzenesulfone derivatives and uses thereof | 达纳-法伯癌症研究所股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| EP-1660466-B1 | METHOD OF OBTAINING URETHANE-PROTECTED N-CARBOXYANHYDRIDES OF ALPHA AMINO ACIDS | ISOCHEM SA (FR) | 2008-01-09 | — | — | EP | disclosed |