Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | BRD1 | O95696 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | TAF1 | P21675 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308375 | 0.76 | BRD4 (0.38) | ALDH1A1MAPK10KDM4EBRD4TRIM24 | |
| SCHEMBL1191685 | 0.75 | MAPK10 (0.45) | ALDH1A1MAPK10MEN1KMT2AUSP2 | |
| SCHEMBL27704682 | 0.74 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL31621835 | 0.74 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL15816469 | 0.72 | ADRA1D (0.51) | ALDH1A1MAPK10MEN1KMT2AMAPT | |
| SCHEMBL6235800 | 0.70 | ADRA1D (0.48) | ALDH1A1MAPK10MEN1KMT2AMAPT | |
| SCHEMBL29001267 | 0.69 | MAPK10 (0.51) | ALDH1A1MAPK10MEN1KMT2AUSP2 | |
| SCHEMBL15815917 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| Ethane SCHEMBL13370815 | 0.67 | ALDH1A1 (0.51) | ALDH1A1MAPK10MEN1KMT2AMAPT | |
| SCHEMBL13689319 | 0.65 | SIGMAR1 (0.39) | ALDH1A1MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010953-A2 | PYRIDINONE DIKETO ACIDS: INHIBITORS OF HIV REPLICATION IN COMBINATION THERAPY | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2008-01-24 | — | — | WO | disclosed |