Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313250 | 0.89 | HPGDS (0.37) | HPGDSS1PR1ELANES1PR3 | |
| SCHEMBL14313174 | 0.89 | HPGDS (0.36) | HPGDS | |
| SCHEMBL14313349 | 0.89 | HPGDS (0.32) | HPGDS | |
| SCHEMBL14313182 | 0.87 | HPGDS (0.50) | HPGDSS1PR1ELANES1PR3 | |
| SCHEMBL14313327 | 0.87 | HPGDS (0.31) | HPGDS | |
| SCHEMBL14312961 | 0.86 | AGTR2 (0.30) | — | |
| SCHEMBL14312864 | 0.85 | HPGDS (0.39) | HPGDSS1PR1 | |
| SCHEMBL14313264 | 0.85 | HPGDS (0.38) | HPGDSS1PR1ELANES1PR3 | |
| SCHEMBL14312819 | 0.85 | AGTR2 (0.31) | HPGDS | |
| SCHEMBL14313030 | 0.84 | MAPK8 (0.33) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |