Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312695 | 0.89 | HPGDS (0.35) | HPGDSHSP90AA1 | |
| SCHEMBL14313257 | 0.88 | HPGDS (0.35) | HPGDS | |
| SCHEMBL14312571 | 0.85 | HPGDS (0.40) | HPGDS | |
| SCHEMBL14313347 | 0.85 | HPGDS (0.37) | HPGDS | |
| SCHEMBL14312653 | 0.85 | HPGDS (0.49) | HPGDSHSP90AA1 | |
| SCHEMBL14313459 | 0.83 | HPGDS (0.42) | HPGDSHSP90AA1 | |
| SCHEMBL14313042 | 0.81 | HPGDS (0.49) | HPGDS | |
| SCHEMBL14312617 | 0.80 | HPGDS (0.59) | HPGDS | |
| SCHEMBL14313148 | 0.78 | HPGDS (0.43) | HPGDS | |
| SCHEMBL14313361 | 0.78 | HPGDS (0.60) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |