Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14313327 | 0.87 | HPGDS (0.31) | HPGDS | |
| SCHEMBL14312870 | 0.87 | HPGDS (0.39) | HPGDSBCHEACHENTRK1 | |
| SCHEMBL14312676 | 0.86 | TGFBR1 (0.32) | HPGDS | |
| SCHEMBL14313407 | 0.86 | HPGDS (0.30) | HPGDS | |
| SCHEMBL14313182 | 0.85 | HPGDS (0.50) | HPGDSBCHEACHEELANENTRK1 | |
| SCHEMBL14313085 | 0.85 | HPGDS (0.39) | HPGDS | |
| SCHEMBL14313347 | 0.85 | HPGDS (0.37) | HPGDS | |
| SCHEMBL14313267 | 0.84 | HPGDS (0.43) | HPGDSBCHEACHEELANENTRK1 | |
| SCHEMBL14313042 | 0.83 | HPGDS (0.49) | HPGDS | |
| SCHEMBL14313348 | 0.81 | HPGDS (0.37) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142516-B1 | PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS | SANOFI SA (FR) | 2012-12-26 | — | — | EP | claimed |