Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488403 | 0.74 | HTR7 (0.61) | HTR7ESR2ESR1PTGS2PTGS1 | |
| SCHEMBL2015788 | 0.74 | HTR7 (0.61) | HTR7PTGS2PTGS1GAATRPA1 | |
| SCHEMBL7885389 | 0.74 | HTR7 (1.00) | HTR7GAAHPGDHDAC3HDAC1 | |
| SCHEMBL8213922 | 0.72 | HTR7 (0.58) | HTR7ESR2ESR1PTGS2PTGS1 | |
| SCHEMBL11775906 | 0.71 | HTR7 (0.52) | HTR7GAATRPA1HPGDHDAC3 | |
| SCHEMBL27798133 | 0.70 | HTR7 (0.56) | HTR7ESR2ESR1PTGS2PTGS1 | |
| Valeric Acid SCHEMBL29009893 | 0.69 | HTR7 (0.66) | HTR7ESR1HPGDLMNA | |
| SCHEMBL28375637 | 0.69 | HTR7 (0.58) | HTR7ESR2ESR1PTGS2PTGS1 | |
| SCHEMBL5178977 | 0.69 | HTR7 (0.89) | HTR7GAANPC1RAB9AHSD17B3 | |
| SCHEMBL7231325 | 0.69 | HTR7 (0.54) | HTR7ESR2ESR1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |