Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884033 | 0.83 | HTR7 (0.47) | HTR7HPGDHDAC3HDAC1HDAC2 | |
| SCHEMBL815083 | 0.79 | PTGS2 (0.57) | PTGS2ESR1ALDH1A1CES2CES1 | |
| SCHEMBL7885389 | 0.76 | HTR7 (1.00) | HTR7GAAHPGDHDAC3HDAC1 | |
| SCHEMBL2015788 | 0.76 | HTR7 (0.61) | HTR7PTGS1PTGS2GAAHPGD | |
| SCHEMBL6324909 | 0.75 | HSD17B3 (0.43) | HTR7PTGS1PTGS2HPGDHSD17B3 | |
| SCHEMBL14313613 | 0.74 | HTR7 (0.59) | HTR7PTGS1PTGS2GAAHPGD | |
| SCHEMBL815888 | 0.73 | CES2 (0.56) | PTGS2ESR1CES2CES1 | |
| SCHEMBL8213922 | 0.73 | HTR7 (0.58) | HTR7PTGS1PTGS2GAAHPGD | |
| SCHEMBL27200589 | 0.73 | HTR7 (0.62) | HTR7GAAHPGDHDAC3HDAC1 | |
| SCHEMBL814748 | 0.72 | CES2 (0.58) | PTGS2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | claimed |
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | disclosed |