SCHEMBL2015788

SCHEMBL2015788

C=C(CCCC)c1ccc(F)cc1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.61
MAOA P21397 4/20 0.48
MAOB P27338 4/20 0.48
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
GAA P10253 1/20 0.45
TRPA1 O75762 1/20 0.45
HPGD P15428 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23891539 0.92 GAA (0.54) HTR7MAOAMAOBGAAHDAC3
SCHEMBL10415441 0.88 MAOA (0.52) HTR7MAOAMAOBGAATRPA1
SCHEMBL7187984 0.82 HSD17B3 (0.60) PTGS1PTGS2
SCHEMBL7193415 0.82 ALDH1A1 (0.44) HTR7PTGS2
SCHEMBL10414514 0.80 HDAC3 (0.45) HTR7MAOAMAOBHDAC3HDAC1
SCHEMBL2011999 0.80 MAOA (0.48) HTR7MAOAMAOBGAAHPGD
SCHEMBL11696345 0.80 LMNA (0.47) HTR7MAOAPTGS2GAANPC1
SCHEMBL10413952 0.80 ALDH1A1 (0.45) HTR7HDAC3HDAC1HDAC2
SCHEMBL14944831 0.79 MAOA (0.44) HTR7MAOAMAOBHPGDNPC1
SCHEMBL20448 0.79 PTGS2 (0.57) MAOAMAOBPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513237-B1 STAIN-BLOCKING AQUEOUS COATING COMPOSITION AKZO NOBEL COATINGS INT BV (NL) 2014-06-18 EP disclosed
US-8709609-B2 Stain-blocking aqueous coating composition AKZO NOVEL COATINGS INTERNATIONAL B.V. (NL) 2014-04-29 US disclosed
EP-2513237-A1 STAIN-BLOCKING AQUEOUS COATING COMPOSITION Akzo Nobel Coatings International B.V. (NL) 2012-10-24 EP disclosed
US-20120244368-A1 STAIN-BLOCKING AQUEOUS COATING COMPOSITION AKZO NOBEL COATING INTERNATIONAL B.V. (NL) 2012-09-27 US disclosed
WO-2011073164-A1 STAIN-BLOCKING AQUEOUS COATING COMPOSITION AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2011-06-23 WO disclosed
US-7638514-B2 Agriculture SYNGENTA CROP PROTECTION, INC. (US) 2009-12-29 US disclosed
US-7638514-B2 Agriculture SYNGENTA CROP PROTECTION, INC. (US) 2009-12-29 US disclosed
US-20070142229-A1 Pesticidally active phenol derivatives SYNGENTA CROP PROTECTION, INC. 2007-06-21 US disclosed
US-20070142229-A1 Pesticidally active phenol derivatives SYNGENTA CROP PROTECTION, INC. 2007-06-21 US disclosed
EP-0197274-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED STYRENES BAYER AG (DE) 1989-01-04 EP disclosed
US-4650910-A CLEAVAGE OF N-ACYL-B-PHENETHYLAMINES WITH BASE BAYER AKTIENGESELLSCHAFT (DE) 1987-03-17 US disclosed
EP-0197274-A1 Process for the preparation of substituted styrenes BAYER AG (DE) 1986-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142229-A1 Pesticidally active phenol derivatives DDT, QSOX1, CHRM1 HTR7 2612/4885MAOA 219/4885MAOB 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.