Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613742 | 0.75 | F2 (0.33) | ATMF2F10F12F7 | |
| SCHEMBL28333347 | 0.74 | MAOA (0.46) | MAOAMAOBEGFRATMUSP2 | |
| SCHEMBL18381166 | 0.73 | MEN1 (0.38) | MAOAMAOBEGFRATMALDH1A1 | |
| SCHEMBL18051463 | 0.73 | F2 (0.38) | MAOBATMF2F10F12 | |
| SCHEMBL21944495 | 0.70 | MAOB (0.42) | MAOAMAOBEGFRALDH1A1LMNA | |
| SCHEMBL12857109 | 0.68 | CES2 (0.48) | EGFRATMUSP2ALDH1A1LMNA | |
| SCHEMBL24947784 | 0.68 | CES2 (0.32) | ATMLMNAPOLBMAPTNPSR1 | |
| SCHEMBL21064096 | 0.67 | CES2 (0.37) | MAOBATMALDH1A1LMNAPOLB | |
| SCHEMBL7767040 | 0.67 | MAOA (0.54) | MAOAMAOBEGFRUSP2ALDH1A1 | |
| SCHEMBL2380219 | 0.66 | MAOA (0.44) | MAOAMAOBEGFRUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504002-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINOKETONES AND OPTICALLY ACTIVE 1,3-AMINOALCOHOLS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-12-19 | — | — | EP | disclosed |