Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 8/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362873 | 0.84 | VCP (0.40) | VCPALDH1A1GLA | |
| SCHEMBL10280031 | 0.83 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL12670478 | 0.82 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL19575551 | 0.81 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL16480089 | 0.80 | HTT (0.35) | — | |
| SCHEMBL14852901 | 0.80 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL12067752 | 0.80 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL14852900 | 0.78 | DRD2 (0.43) | CHRM3 | |
| SCHEMBL16503556 | 0.78 | DRD2 (0.43) | CHRM3 | |
| SCHEMBL13635193 | 0.78 | CHRM3 (0.33) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322837-A1 | AMIDE COMPOUND AND MEDICINAL USE THEREOF | SLC10A2, SLC10A1, SLC5A11 | AKR1C3 3159/4885AKR1C1 2961/4885VCP 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.