Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | MASP2 | O00187 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432138 | 0.91 | TACR1 (0.45) | TACR1MASP2 | |
| SCHEMBL1432208 | 0.91 | TACR1 (0.44) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1432145 | 0.91 | TACR1 (0.46) | TACR1MASP2PPIB | |
| SCHEMBL1432383 | 0.89 | TACR1 (0.46) | TACR1MASP2 | |
| SCHEMBL1431881 | 0.88 | MASP2 (0.41) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1432069 | 0.88 | MEN1 (0.49) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1435074 | 0.87 | TACR1 (0.48) | TACR1 | |
| SCHEMBL1431863 | 0.85 | MEN1 (0.48) | MASP2KMT2AMEN1PPIBITGB1 | |
| SCHEMBL1431634 | 0.85 | MEN1 (0.41) | TACR1MASP2KMT2AMEN1PPIB | |
| SCHEMBL1432518 | 0.85 | MEN1 (0.41) | TACR1MASP2KMT2AMEN1PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |