Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MASP2 | O00187 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.40 |
| ▸ | XIAP | P98170 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432725 | 0.91 | TACR1 (0.46) | TACR1SCN9ACYP3A4MASP2SCN10A | |
| SCHEMBL1432208 | 0.90 | TACR1 (0.44) | TACR1SCN9AMASP2XIAP | |
| SCHEMBL1431630 | 0.89 | TACR1 (0.43) | TACR1MASP2 | |
| SCHEMBL1432138 | 0.88 | TACR1 (0.45) | TACR1MASP2 | |
| SCHEMBL1432145 | 0.88 | TACR1 (0.46) | TACR1MASP2PLGPRSS1PRSS2 | |
| SCHEMBL1432069 | 0.85 | MEN1 (0.49) | TACR1MASP2 | |
| SCHEMBL1435074 | 0.84 | TACR1 (0.48) | TACR1 | |
| SCHEMBL1431881 | 0.84 | MASP2 (0.41) | TACR1CYP3A4MASP2 | |
| SCHEMBL1431634 | 0.83 | MEN1 (0.41) | TACR1MASP2XIAP | |
| SCHEMBL1432518 | 0.83 | MEN1 (0.41) | TACR1MASP2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |