Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432069 | 0.92 | MEN1 (0.49) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1431863 | 0.90 | MEN1 (0.48) | MASP2MEN1KMT2APPIBITGB1 | |
| SCHEMBL1432824 | 0.90 | MASP2 (0.41) | MASP2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1431634 | 0.89 | MEN1 (0.41) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1432518 | 0.89 | MEN1 (0.41) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1432215 | 0.88 | TACR1 (0.45) | MASP2TACR1 | |
| SCHEMBL1431630 | 0.88 | TACR1 (0.43) | MASP2MEN1KMT2APPIBTACR1 | |
| SCHEMBL1433005 | 0.87 | CTSV (0.47) | MASP2KMT2ATACR1ITGB1ITGA4 | |
| SCHEMBL1432054 | 0.87 | MEN1 (0.40) | MASP2MEN1KMT2APPIB | |
| SCHEMBL1432208 | 0.86 | TACR1 (0.44) | MASP2MEN1KMT2APPIBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |