Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 9/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14248067 | 0.86 | CTSK (0.42) | CTSKCTSSCTSL | |
| SCHEMBL14248139 | 0.86 | CTSK (0.42) | CTSKCTSSCTSL | |
| SCHEMBL14317721 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL15005809 | 0.82 | CTSK (0.37) | CTSKCTSSPSENEN | |
| SCHEMBL8466502 | 0.79 | CTSS (0.59) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL8466501 | 0.79 | CTSS (0.59) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL13830117 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL15672734 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL2721327 | 0.75 | CTSK (0.55) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 | |
| SCHEMBL13956771 | 0.75 | CTSK (0.55) | SMN1; SMN2CTSKCTSSCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2721053-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-10-19 | — | — | EP | disclosed |
| US-20130142754-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2013-06-06 | — | — | US | disclosed |
| WO-2012173983-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142754-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, GOT1 | SMN1; SMN2 4455/4885CTSK 945/4885CTSS 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.