Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431488 | 0.84 | MALT1 (0.39) | MALT1MASP2 | |
| SCHEMBL3153097 | 0.83 | F2 (0.49) | F2MEN1KMT2AMASP2PLA2G1B | |
| SCHEMBL3155114 | 0.82 | MAPK14 (0.43) | HPGDALDH1A1F2MEN1KMT2A | |
| SCHEMBL1431882 | 0.82 | MAPK14 (0.43) | HPGDALDH1A1F2MEN1KMT2A | |
| SCHEMBL1433035 | 0.81 | F2 (0.40) | F2MASP2BCHE | |
| SCHEMBL1432382 | 0.81 | F2 (0.40) | ALDH1A1F2MEN1KMT2AMASP2 | |
| SCHEMBL3139300 | 0.81 | MASP2 (0.47) | MEN1KMT2AMALT1MASP2CYP2C19 | |
| SCHEMBL1431762 | 0.80 | MASP2 (0.43) | MALT1MASP2 | |
| SCHEMBL1431704 | 0.80 | MASP2 (0.43) | MALT1MASP2 | |
| SCHEMBL1432197 | 0.80 | F2 (0.40) | F2MEN1KMT2AMASP2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |