Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432197 | 0.91 | F2 (0.40) | F2CCR2OPRM1OPRL1MASP2 | |
| SCHEMBL1432382 | 0.90 | F2 (0.40) | F2CCR2OPRM1OPRL1MASP2 | |
| SCHEMBL1431749 | 0.88 | MASP2 (0.40) | F2OPRM1MASP2ROCK2 | |
| SCHEMBL1432188 | 0.87 | MASP2 (0.39) | OPRM1OPRL1MASP2ROCK2 | |
| SCHEMBL1432510 | 0.84 | MASP2 (0.38) | MASP2 | |
| SCHEMBL1432651 | 0.83 | NAMPT (0.46) | MASP2 | |
| SCHEMBL1433112 | 0.83 | KCNQ2 (0.42) | F2CCR2TACR1 | |
| SCHEMBL3155973 | 0.81 | MAPK14 (0.45) | F2MASP2 | |
| SCHEMBL1433033 | 0.81 | MAPK14 (0.45) | F2MASP2 | |
| SCHEMBL1431885 | 0.81 | HPGD (0.39) | F2MASP2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | claimed |
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |