Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432382 | 0.92 | F2 (0.40) | F2CCR2OPRM1OPRL1MASP2 | |
| SCHEMBL1433035 | 0.91 | F2 (0.40) | F2CCR2OPRM1OPRL1MASP2 | |
| SCHEMBL1431810 | 0.88 | MASP2 (0.39) | OPRM1MASP2MEN1KMT2ACDK8 | |
| SCHEMBL1433112 | 0.84 | KCNQ2 (0.42) | F2CCR2KCNQ2 | |
| SCHEMBL1432194 | 0.82 | MAPK14 (0.44) | F2MASP2MAPK14 | |
| SCHEMBL3147894 | 0.82 | MAPK14 (0.44) | F2MASP2MAPK14 | |
| SCHEMBL1431682 | 0.80 | MASP2 (0.40) | MASP2MEN1KMT2AROCK2 | |
| SCHEMBL1432618 | 0.80 | NAMPT (0.41) | CCR2MASP2MEN1KMT2A | |
| SCHEMBL1431885 | 0.80 | HPGD (0.39) | F2MASP2MEN1KMT2ABCHE | |
| SCHEMBL1432369 | 0.80 | MASP2 (0.38) | MASP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |