Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150073 | 0.77 | MASP2 (0.40) | PPIBALDH1A1KCNH2DPP4LMNA | |
| SCHEMBL1431936 | 0.75 | F2 (0.39) | PPIBTLR2ALDH1A1KCNH2DPP4 | |
| SCHEMBL3258183 | 0.69 | DPP4 (0.40) | PPIBALDH1A1KCNH2DPP4PDPK1 | |
| SCHEMBL3154107 | 0.69 | PPIB (0.40) | PPIBALDH1A1KCNH2DPP4LMNA | |
| SCHEMBL1431769 | 0.68 | DPP4 (0.39) | PPIBALDH1A1KCNH2DPP4LMNA | |
| SCHEMBL1432630 | 0.68 | DPP4 (0.39) | PPIBALDH1A1KCNH2DPP4LMNA | |
| SCHEMBL1433063 | 0.68 | HDAC1 (0.44) | KCNH2DPP4MAPTMEN1KMT2A | |
| SCHEMBL1432780 | 0.68 | F2 (0.42) | ALDH1A1KCNH2DPP4LMNAMEN1 | |
| SCHEMBL1432209 | 0.68 | F2 (0.42) | ALDH1A1KCNH2DPP4LMNAMEN1 | |
| SCHEMBL1431525 | 0.67 | PPIB (0.39) | PPIBTLR2ALDH1A1KCNH2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |