Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431936 | 0.92 | F2 (0.39) | PPIBF2ALDH1A1SMN1; SMN2TLR2 | |
| SCHEMBL3154107 | 0.84 | PPIB (0.40) | PPIBF2ALDH1A1SMN1; SMN2MASP2 | |
| SCHEMBL1431965 | 0.78 | EHMT2 (0.43) | TLR2MASP2EHMT2 | |
| SCHEMBL1432565 | 0.78 | EHMT2 (0.45) | TLR2MASP2EHMT2 | |
| SCHEMBL1902464 | 0.77 | MASP2 (0.39) | TLR2MASP2 | |
| SCHEMBL1899812 | 0.77 | MASP2 (0.39) | TLR2MASP2 | |
| SCHEMBL1432274 | 0.75 | AAK1 (0.38) | HDAC1MASP2 | |
| SCHEMBL1901340 | 0.75 | PDPK1 (0.39) | TLR2MASP2EHMT2 | |
| SCHEMBL1907783 | 0.75 | PDPK1 (0.38) | TLR2HDAC1MASP2 | |
| SCHEMBL1431876 | 0.75 | MASP2 (0.43) | TLR2MASP2EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |