Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14320257 | 1.00 | ALDH1A1 (0.44) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL12482005 | 0.87 | ALDH1A1 (0.37) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL14329685 | 0.86 | ALDH1A1 (0.36) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL14328155 | 0.84 | ALDH1A1 (0.35) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL14328142 | 0.83 | ALDH1A1 (0.38) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL14328168 | 0.83 | ALDH1A3 (0.34) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL14329620 | 0.80 | APP (0.37) | ALDH1A1ALDH3A1ALDH1A3MEN1KMT2A | |
| SCHEMBL5858618 | 0.79 | — | — | |
| SCHEMBL14328150 | 0.77 | CHRM2 (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8977050 | 0.74 | MEN1 (0.32) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120329865-A1 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF | CORNING INCORPORATED | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329865-A1 | MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF | KCNH2, KCNJ2, KCNH3 | ALDH1A1 1574/4885ALDH3A1 1577/4885ALDH1A3 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.