Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 10/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.42 |
| ▸ | KLK1 | P06870 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 11/20 | 0.42 |
| ▸ | CTSV | O60911 | 10/20 | 0.42 |
| ▸ | CTSS | P25774 | 10/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141395 | 0.92 | CTSB (0.45) | CTSBKLKB1KLK1CTSLCTSV | |
| SCHEMBL1432124 | 0.92 | CTSB (0.45) | CTSBKLKB1KLK1CTSLCTSV | |
| SCHEMBL1431649 | 0.90 | HTT (0.43) | KLKB1KLK1MASP2 | |
| SCHEMBL1434219 | 0.90 | KLKB1 (0.42) | CTSBKLKB1KLK1HTRA1MASP2 | |
| SCHEMBL1432562 | 0.88 | MME (0.43) | KLKB1HTRA1MASP2 | |
| SCHEMBL1432022 | 0.88 | MME (0.43) | KLKB1HTRA1MASP2 | |
| SCHEMBL1431886 | 0.87 | PSMB5 (0.49) | KLKB1CTSLMASP2 | |
| SCHEMBL1432492 | 0.87 | KLKB1 (0.43) | CTSBKLKB1KLK1CTSLCTSV | |
| SCHEMBL3154156 | 0.86 | KLKB1 (0.50) | CTSBKLKB1KLK1CTSLCTSV | |
| SCHEMBL1431801 | 0.86 | KLKB1 (0.50) | CTSBKLKB1KLK1CTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |