Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | KLK1 | P06870 | 3/20 | 0.49 |
| ▸ | CTSV | O60911 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431801 | 1.00 | KLKB1 (0.50) | KLKB1CTSBKLK1CTSVCTSL | |
| SCHEMBL3137925 | 0.91 | KLKB1 (0.53) | KLKB1KLK1 | |
| SCHEMBL3137935 | 0.91 | KLKB1 (0.53) | KLKB1KLK1 | |
| SCHEMBL1901841 | 0.90 | CTSB (0.48) | KLKB1CTSBKLK1CTSVCTSL | |
| SCHEMBL1901838 | 0.90 | CTSB (0.48) | KLKB1CTSBKLK1CTSVCTSL | |
| SCHEMBL3138289 | 0.89 | KLKB1 (0.53) | KLKB1KLK1 | |
| SCHEMBL3138276 | 0.89 | KLKB1 (0.53) | KLKB1KLK1 | |
| SCHEMBL1433146 | 0.88 | CTSB (0.48) | KLKB1CTSBKLK1CTSVCTSL | |
| SCHEMBL3141558 | 0.88 | CTSB (0.48) | KLKB1CTSBKLK1CTSVCTSL | |
| SCHEMBL3141395 | 0.88 | CTSB (0.45) | KLKB1CTSBKLK1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | KLKB1 3491/4885CTSB 2784/4885KLK1 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.