Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 10/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612215 | 0.73 | CYP1A2 (0.65) | HSD17B10TP53ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8809191 | 0.73 | NAMPT (0.67) | HSD17B10TP53ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27315062 | 0.72 | ALDH1A1 (0.67) | HSD17B10TP53ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13947029 | 0.72 | NAMPT (1.00) | RAB9ANPC1NAMPTLMNAHIF1A | |
| SCHEMBL9906904 | 0.71 | RAB9A (0.65) | HSD17B10TP53ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL967245 | 0.71 | RAB9A (0.72) | TP53ALDH1A1RAB9APKMNPC1 | |
| SCHEMBL11213715 | 0.71 | RAB9A (0.72) | TP53ALDH1A1RAB9APKMNPC1 | |
| SCHEMBL28055749 | 0.71 | POLB (0.66) | HSD17B10TP53ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13966172 | 0.71 | CYP11B2 (0.64) | ALDH1A1NPC1NAMPTHTTKDM4E | |
| SCHEMBL20176883 | 0.71 | NAMPT (0.66) | HSD17B10TP53ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300470-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS GABA-A RECEPTOR MODULATORS | Sepracor Inc. (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009143156-A2 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS | SEPRACOR INC. (US) | 2009-11-26 | — | — | WO | disclosed |